Regenerative medicine, stem cells

regenerative medicine, stem cells, biomedic oncological clinic spain

Regenerative Medicine is the new medicine of XXI century which is able to repair damaged tissue using similar mechanisms to the body uses naturally to renew different cell types. The old cells must die to be renewed by new ones that cover the same function. Our body performs functions of regeneration, repairing and renewal of tissues, functions that are limited according to our level of degeneration or cell damage.

The new developments in Regenerative Biological Medicine and Tissue Bio-Engineering have given way to a new and more natural medicine, more efficient and effective that promotes our natural regenerative mechanisms at the expense of the old medicine that is trying to repair what it is damaged. In this regard, new knowledge is being applied in this medicine connected to adult stem cells, growth factors, certain cytokines (which regulate the communication among cells), proteic fractions and Stromal Vascular Fraction (SVF) extracted from fat tissue and bone marrow.

What is the SVF (Stromal vascular fraction) from fat tissue?

This is a sample compound of different type of cells with a great ability to regenerate damaged tissue which has being worn away or is too old biologically. We can extract the SVF from the bone marrow but it is much easier to do it from the abdominal fat with microsurgery techniques such as liposuction.

Within a SVF sample we can find different types of cells such as: endothelial cells which create tissue to cover many organs inside or outside of them, pre-adipocytes (cells that accumulates fat in their early stages), T-cells of the immune system, hematopoietic stem cells (that can convert themselves in any blood cell), macrophages which are a type of immune cell and can literally swallow any pathogenic microorganism.

Stem cells are cells that can be anywhere in the body with a total or partial ability to differentiate themselves in specific cells from different type of tissues. Thus Stem Cells can be divided into three types: there are Totipotential Stem Cells, which can create any type of cell, Pluripotential Stem Cells that can create three types of cell lineages and the last type is the Multipotential Stem Cells that can generate just the same type of cells as the first come from.

Reasons to use the SVF from fat more than the one extracted from the bone marrow

• It is easier to extract the SVF from the fat through a minor surgery and therefore the discomfort after surgery is less.
• In this fraction, the quantity and workability is greater.
• The ability in both types of fractions is pretty the same.

Apllications of SVF within regenerative medicine

• In traumatology, we can accelerate the lesion recovery.
• Applications in Esthetic Medicine and Plastic Surgery.
• In Odontology, we can create bone mass to anchor implants.
• Maxillofacial regeneration through the generation of bone mass (osteogenesis).
• Heart and Endocrine Glands Regeneration.
• And much more applications that are being experimented at this moment all over the world.

Regenerative Medicine is developing and advancing at a great pace to treat many neurodegenerative diseases such as Alzheimer, Parkinson, Dementia, and Multiple Sclerosis among many others. Other diseases can be also treated with stem cells therapy such as Heart diseases, Myocardial infarction (Heart Attacks), or heart failure, arthritis or osteo-arthritis, brain damages, diffuse brain injuries, spine injuries, kidney failure, and diabetes type II and much more.

Over time, the list of diseases that can be treated with this therapy will grow significantly because the regenerative medicine is developing continuously and quickly all over the world.

Written by Dra. Maria Eudoxia Lopez Peral

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